Pattern formation in the zebrafish retina

Semin Cell Dev Biol. 2001 Dec;12(6):485-90. doi: 10.1006/scdb.2001.0272.


During the past 15 years, the zebrafish has become established as a genetic model organism to study vertebrate development. It is particularly well suited for the analysis of the retina, and several genetic screens have yielded a large number of mutants affecting retinal development. Most of these mutants still await thorough analysis and molecular characterization, but work on a handful of genes has already generated interesting results that shed some light on patterning mechanisms employed in the vertebrate retina.

Publication types

  • Review

MeSH terms

  • Animals
  • Autonomic Nervous System / embryology*
  • Body Patterning*
  • Cell Differentiation
  • Hedgehog Proteins
  • Membrane Proteins / metabolism
  • Models, Animal
  • Receptors, Notch
  • Retina / embryology*
  • Signal Transduction
  • Trans-Activators / genetics*
  • Trans-Activators / physiology
  • Zebrafish / embryology*


  • Hedgehog Proteins
  • Membrane Proteins
  • Receptors, Notch
  • Trans-Activators