Regulating microtubule properties by modifying their organizing minus ends

Mol Cell. 2001 Nov;8(5):931-2. doi: 10.1016/s1097-2765(01)00394-x.

Abstract

In the November 2001 issue of Developmental Cell, Vogel et al. describe that the budding yeast gamma-tubulin, Tub4p, is phosphorylated at a conserved tyrosine in G1 phase of the cell cycle. The results suggest that gamma-tubulin phosphorylation regulates the number and dynamics of microtubules.

Publication types

  • Review

MeSH terms

  • Cell Cycle / physiology
  • Fungal Proteins / genetics
  • Fungal Proteins / metabolism
  • Microtubule-Organizing Center / metabolism*
  • Microtubules / metabolism*
  • Phosphorylation
  • Saccharomyces cerevisiae Proteins*
  • Tubulin / genetics
  • Tubulin / metabolism*

Substances

  • Fungal Proteins
  • Saccharomyces cerevisiae Proteins
  • TUB4 protein, S cerevisiae
  • Tubulin