Predictors of deterioration among patients with substance-use disorders

J Clin Psychol. 2001 Dec;57(12):1403-19. doi: 10.1002/jclp.1105.


The purpose of this study was to identify patients with substance-use disorders who deteriorate during treatment, and to examine baseline predictors of deterioration. Three groups of 872 patients each, matched on number of problems at baseline, were selected from a larger sample based on their treatment outcome (improved, nonresponsive, deteriorated). Deterioration was predicted by younger age and African-American race; four aspects of patients' history (psychiatric symptoms, arrests, prior drug treatment, and recent inpatient or residential care); and having no close friends. Patients who had both an alcohol and a drug diagnosis, a personality-disorder diagnosis, and those who had a shorter episode of care and fewer outpatient-mental-health visits, also were more likely to deteriorate.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • African Americans / psychology*
  • Age Factors
  • Crime
  • Diagnosis, Dual (Psychiatry)
  • Disease Progression
  • Female
  • Hospitalization
  • Humans
  • Male
  • Personality Disorders
  • Predictive Value of Tests
  • Prognosis
  • Risk Factors
  • Social Alienation*
  • Social Support
  • Substance-Related Disorders / psychology*
  • Treatment Outcome