The purpose of this study was to describe and analyze the various appearances of hepatic angiomyolipoma (AML) on the two-phase contrast scans of spiral CT and find out the valuable signs suggesting the diagnosis. Spiral CT scanning of pre- and post-contrast arterial phase, portal venous phase were performed in 12 cases. We found that 11 of 12 lesions appeared as hypodense, the other one appeared as slightly hyperdense on pre-contrast CT scans. On the arterial phase, 11 lesions were markedly enhanced, with the central vasculature opacification in eight lesions; the only other lesion showed no marked enhancement, but with massive vessels seen within the lesion. On the portal venous phase, eight lesions remained in enhancement with the central vessels also seen in six lesions. Our results revealed that two-phase contrast scanning could demonstrate some characteristic features of AML, such as fat components within the lesions, hypervascular tumors, the absence of capsule. Especially the central vessels within the lesions suggested strongly the diagnosis of AML. As for atypical cases, the diagnosis remained difficult and should be differentiated from other hypervascular lesions by means of other imaging modalities or needle puncture biopsy.