RNA interference by feeding in Paramecium

Trends Genet. 2002 Jan;18(1):11-2. doi: 10.1016/s0168-9525(01)02548-3.

Abstract

RNA interference can be induced very efficiently by feeding the ciliate Paramecium with bacteria engineered to express double-stranded RNA, opening the possibility of large-scale functional screening in this unicell.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Gene Silencing
  • Paramecium / genetics*
  • Phenotype
  • RNA, Double-Stranded / administration & dosage
  • RNA, Double-Stranded / genetics
  • RNA, Protozoan / administration & dosage
  • RNA, Protozoan / genetics*

Substances

  • RNA, Double-Stranded
  • RNA, Protozoan