[Vitiligo, hepato-splenomegaly, and goitre after working with paratertiary butylphenol (author's transl)]

Abstract

In three men vitiligo-like skin changes, enlargement of liver and spleen and diffuse goitre (grade II) with increased TSH secretion developed within one to two years of their having started work in a factory producing paratertiary butylphenol. These observations also tend to confirm the often discussed pathogenetic connection between vitiligo and thyroid disease.