The Salmonella pathogenicity island-1 type III secretion system

Microbes Infect. Nov-Dec 2001;3(14-15):1281-91. doi: 10.1016/s1286-4579(01)01488-5.


Salmonella pathogenicity island 1 (SPI1) encodes a type III secretion system that is required for virulence during the intestinal phase of infection. The expression of SPI1 genes is controlled by many global regulatory pathways that affect the expression/activity of transcriptional regulators encoded on SPI1.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Gene Expression Regulation, Bacterial*
  • Intestines / microbiology
  • Mice
  • Salmonella Infections, Animal / microbiology*
  • Salmonella typhimurium / genetics
  • Salmonella typhimurium / metabolism
  • Salmonella typhimurium / pathogenicity*
  • Signal Transduction


  • Bacterial Proteins
  • Spi1 protein, Salmonella