[Occurrence of beta-lactamase type ESBL and IBL in Pseudomonas aeruginosa rods]

Med Dosw Mikrobiol. 2001;53(1):45-51.
[Article in Polish]


The aim of the study was to determine extended spectrum beta-lactamases (ESBL) and inducible beta-lactamases (IBL) among Pseudomonas aeruginosa strains. A total of 43 strains isolated from humans (6), hospital sink (1), fish (15), cattle (5), swine (5), dog (1), redder (1) fur animals (9) were studied. ESBL-producing strains were detected with double disc diffusion test according to Jarlier et al. (8). Clavulonate and tazobactam were used as the inhibitors of ESBL. Inducible beta-lactamases were determined using double disc method according to Sanders (15). Cefoxitin was the inductor of these beta-lactamases. The susceptibility study was carried out using the disc diffusion method according to NCCLS standards. A total of 8 ESBL (18.6% of all strains) and 31 (72%) IBL producing strains were detected. The obtained results indicate the necessity of monitoring of ESBL- and IBL-producing strains of Pseudomonas aeruginosa.

MeSH terms

  • Animals
  • Cattle
  • Cefoxitin / pharmacology
  • Clavulanic Acid / pharmacology
  • Dogs
  • Fishes
  • Humans
  • Microbial Sensitivity Tests
  • Penicillanic Acid / analogs & derivatives*
  • Penicillanic Acid / pharmacology
  • Pseudomonas aeruginosa / classification
  • Pseudomonas aeruginosa / enzymology*
  • Species Specificity
  • Swine
  • Tazobactam
  • beta-Lactamases / metabolism*


  • Clavulanic Acid
  • Cefoxitin
  • Penicillanic Acid
  • beta-Lactamases
  • Tazobactam