[Effect of the treatment with femoston on the cardiovascular system in postmenopausal women]

Ter Arkh. 2001;73(10):38-40.
[Article in Russian]

Abstract

Aim: To assess femoston effects on the cardiovascular system in postmenopause.

Material and methods: Cardiovascular effects of femoston were studied in 20 postmenopausal women with menopausal syndrome. 70% patients had arterial hypertension. Cardiovascular system was examined before the treatment and after three treatment months using 24-h monitoring of arterial pressure, echocardiography, photoplethysmography, conjunctival biomicroscopy, central hemodynamics tests.

Results: In the course of femoston treatment menopausal manifestations relieved, arterial pressure was lowering. 3-month treatment has improved parameters of central and peripheral hemodynamics: total peripheral vascular resistance significantly fell, stroke and minute blood volumes, cardiac indexrose, tissue blood flow and microcirculation improved.

Conclusion: Femoston produces positive changes in cardiovascular system, vascular tone, microcirculation and arterial pressure.

Publication types

  • Clinical Trial
  • English Abstract

MeSH terms

  • 20-alpha-Dihydroprogesterone / therapeutic use*
  • Cardiovascular System / drug effects*
  • Drug Combinations
  • Estrogen Replacement Therapy*
  • Estrogens / therapeutic use*
  • Female
  • Hemodynamics / drug effects
  • Humans
  • Hypertension / drug therapy
  • Middle Aged
  • Postmenopause*

Substances

  • Drug Combinations
  • Estrogens
  • 20-alpha-Dihydroprogesterone