Biocompatibility and state fatigue behavior of glassy carbon

J Biomed Mater Res. 1975 Jan;9(1):111-20. doi: 10.1002/jbm.820090111.

Abstract

1. The normal stages of bone modeling and remodeling occur following the implantation of carbon plugs. 2. Glassy carbon bars aged in vivo for five months did not undergo statistically significant weakening. 3. Glassy carbon does undergo static fatigue when aged in a simulated biological environment. However, the conditions necessary to cause this failure are extreme. 4. Minimal tissue response was seen to the presence of the carbon.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Biocompatible Materials* / pharmacology
  • Bone Regeneration
  • Bone and Bones / anatomy & histology
  • Bone and Bones / drug effects
  • Carbon* / pharmacology
  • Glass*
  • Rabbits
  • Stress, Mechanical
  • Time Factors

Substances

  • Biocompatible Materials
  • Carbon