Contemporary management of ovarian cancer

Obstet Gynecol Clin North Am. 2001 Dec;28(4):759-73. doi: 10.1016/s0889-8545(05)70234-5.

Abstract

Major advances in treatment for epithelial ovarian cancer have occurred over the last decade, giving hope to patients and families. Surgery remains a cornerstone of therapy. In early-stage epithelial ovarian cancer, a meticulous staging procedure should be performed to aid in determining patients who require appropriate adjuvant therapy and patients who can be monitored. The patient with advanced epithelial ovarian cancer significantly benefits from aggressive cytoreductive surgery and chemotherapy, affording the patient higher rates of complete response and partial response. In the new millenium, new therapeutic modalities should enhance the current response rates.

Publication types

  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cisplatin / administration & dosage
  • Cyclophosphamide / administration & dosage
  • Female
  • Humans
  • Hysterectomy / methods
  • Infusions, Parenteral / methods
  • Melphalan / administration & dosage
  • Middle Aged
  • Neoplasm Staging
  • Ovarian Neoplasms / therapy*
  • Reoperation
  • Second-Look Surgery

Substances

  • Cyclophosphamide
  • Cisplatin
  • Melphalan