Peculiarities in the endocrine response to insulin stress in early infantile autism

J Nerv Ment Dis. 1975 Sep;161(3):180-4. doi: 10.1097/00005053-197509000-00005.

Abstract

Autistic children subjected to the stress of insulin-induced hypoglycemia showed slower recovery of blood glucose, and faster and intractable cortisol response in the 3 hours following the stress. These data suggest that autistic children over-react to this stressor and support clinical evidence of stress intolerance. It is suggested that this peculiarity may be implicated in an explanation of the abnormal behavior seen in this disorder.

MeSH terms

  • Adolescent
  • Autistic Disorder / complications
  • Autistic Disorder / metabolism
  • Autistic Disorder / physiopathology*
  • Blood Glucose / metabolism
  • Child
  • Child, Preschool
  • Female
  • Growth Hormone / metabolism
  • Humans
  • Hydrocortisone / metabolism
  • Hypoglycemia / chemically induced
  • Hypoglycemia / complications
  • Hypoglycemia / metabolism
  • Insulin*
  • Male
  • Stress, Physiological / complications

Substances

  • Blood Glucose
  • Insulin
  • Growth Hormone
  • Hydrocortisone