Construction of comparative cytogenetic maps of the Chinese hamster to mouse, rat and human

Chromosome Res. 2001;9(8):641-8. doi: 10.1023/a:1012952223509.

Abstract

We constructed comparative cytogenetic maps of the Chinese hamster to mouse, rat and human by fluorescence in-situ hybridization using 36 cDNA clones of mouse, rat, Syrian hamster, Chinese hamster and human functional genes. In this study, 30 out of the 36 genes were newly mapped to Chinese hamster chromosomes. The chromosomal homology of the Chinese hamster was identified and arranged in 19, 19 and 18 segments of conserved synteny in mouse, rat and human, respectively. Additionally, two of the 19 segments homologous to mouse chromosomes were initially identified in this study.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Banding
  • Chromosomes*
  • Chromosomes, Human*
  • Conserved Sequence
  • Cricetinae
  • Cricetulus / genetics*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Mice / genetics*
  • Physical Chromosome Mapping
  • Rats / genetics*
  • Sequence Homology, Nucleic Acid
  • Synteny