Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins?

Dev Cell. 2002 Jan;2(1):6-7. doi: 10.1016/s1534-5807(01)00117-4.


Matrix metalloproteinases are enzymes that regulate tissue behavior by interactions with extracellular matrix proteins. RECK, a membrane-anchored inhibitor of MMPs was recently characterized for its role in development, tissue homeostasis, and for tumor angiogenesis.

Publication types

  • Review

MeSH terms

  • Cell Adhesion / physiology
  • Eukaryotic Cells / cytology
  • Eukaryotic Cells / enzymology
  • Matrix Metalloproteinases / metabolism*
  • Tumor Suppressor Proteins / metabolism*


  • Tumor Suppressor Proteins
  • Matrix Metalloproteinases