Milk banking: the influence of storage procedures and subsequent processing on immunologic components of human milk

Adv Nutr Res. 2001;10:389-404. doi: 10.1007/978-1-4615-0661-4_19.


The immunoprotective constituents of human milk are stable when stored at room temperature for 8 hours, when stored at 0 degree-4 degrees C for three days, or when frozen at -20 degrees C for 12 months. They are also stable during pasteurization at 56 degrees C for 30 minutes. Sonification may reduce levels of sIgA and lysozyme and the ability of milk to inhibit growth of E coli. The number of cells in human milk is reduced by storage, freezing, pasteurizing, microwaving and sonification, and the functional capacity of surviving cells is also reduced.

Publication types

  • Review

MeSH terms

  • Cold Temperature / adverse effects
  • Food Handling / methods*
  • Food Handling / standards
  • Food Preservation / methods
  • Food Preservation / standards*
  • Freezing
  • Hot Temperature / adverse effects
  • Humans
  • Milk Banks* / standards
  • Milk, Human / cytology
  • Milk, Human / immunology*
  • Time Factors