Early lung cancer action project: annual screening using single-slice helical CT

Ann N Y Acad Sci. 2001 Dec;952:124-34. doi: 10.1111/j.1749-6632.2001.tb02733.x.

Abstract

The advent of helical CT imaging held promise for the early diagnosis, and thereby, for enhanced curability of lung cancer--a highly fatal disease. In 1993, the Early Lung Cancer Action Project (ELCAP) was initiated and experimentally screened a cohort of 1,000 high-risk persons. Here we summarize the results of the baseline and annual repeat CT screening of these 1,000 subjects. CT-based screening (compared to traditional radiology) was clearly shown to enhance the detection of lung cancer at earlier and more curable stages. A discussion follows of the meaning of the results and possible future screening protocols.

Publication types

  • Evaluation Study
  • Multicenter Study
  • Review

MeSH terms

  • Aged
  • Calcinosis / diagnosis
  • Calcinosis / diagnostic imaging
  • Calcinosis / epidemiology
  • Cohort Studies
  • Female
  • Forecasting
  • Humans
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / prevention & control*
  • Male
  • Mass Screening / methods*
  • Mass Screening / statistics & numerical data
  • Middle Aged
  • New York / epidemiology
  • Patient Dropouts
  • Program Evaluation
  • Smoking
  • Solitary Pulmonary Nodule / diagnosis
  • Solitary Pulmonary Nodule / diagnostic imaging
  • Solitary Pulmonary Nodule / epidemiology
  • Tomography, X-Ray Computed / methods*