Abstract
Silybin (I), silydianin (II) and silychristin (III), the main constituents of silymarin, inhibit the formation of prostaglandins in vitro. The inhibition is log-linearly dependent on the concentration of the effectors.
MeSH terms
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Animals
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Cyclooxygenase Inhibitors*
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Flavonoids / pharmacology*
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Kinetics
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Male
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Rats
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Silymarin / pharmacology*
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Stomach / enzymology*
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Structure-Activity Relationship
Substances
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Cyclooxygenase Inhibitors
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Flavonoids
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Silymarin