Evidence for a light-induced H(+) conductance in the eye of the green alga Chlamydomonas reinhardtii

Biophys J. 2002 Feb;82(2):740-51. doi: 10.1016/S0006-3495(02)75436-2.

Abstract

Rhodopsin-mediated photoreceptor currents, I(P), of the unicellular alga Chlamydomonas reinhardtii were studied under neutral and acidic conditions. We characterized the kinetically overlapping components of the first, flash-induced inward current recorded from the eye, I(P1), as a low- and high-intensity component, I(P1a) and I(P1b), respectively. They peak between 1 and 10 ms after the light-flash and are both likely to be carried by Ca(2+). I(P1a) and I(P1b) exhibit half-maximal photon flux densities, Q(1/2), of approximately 0.14 and 58 microE m(-2), and maximal amplitudes of approximately 4.9 and 38 pA, respectively. At acidic extracellular pH values (pH 3-5), both I(P1) currents are followed by distinct H(+) currents, I(P2a) and I(P2b), with maxima after approximately 5 and 100 ms, respectively. Because the Q(1/2) values of I(P1b) and I(P2b) virtually coincide with Q(1/2) of rhodopsin bleaching, we suggest that the respective conductances G(1b) and G(2b) are closely coupled to the rhodopsin, whereas the low light-saturating conductances G(1a) and G(2a) reflect transducer-activated states of a second rhodopsin photoreceptor system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biophysical Phenomena
  • Biophysics
  • Calcium / metabolism
  • Chlamydomonas reinhardtii / metabolism*
  • Electrophysiology
  • Hydrogen / metabolism*
  • Hydrogen-Ion Concentration
  • Kinetics
  • Light
  • Photoreceptor Cells, Invertebrate / metabolism*
  • Potassium / metabolism
  • Rhodopsin / metabolism
  • Thermodynamics

Substances

  • Hydrogen
  • Rhodopsin
  • Potassium
  • Calcium