Clinical factors in the prognosis of complex regional pain syndrome type I after stroke: a prospective study

Am J Phys Med Rehabil. 2002 Jan;81(1):34-9. doi: 10.1097/00002060-200201000-00006.


Objective: To evaluate clinical prognostic factors of complex regional pain syndrome type I (CRPS I) in patients with stroke in an attempt to improve the Perrigot score, which does not include shoulder subluxation, unilateral neglect, or depression.

Design: This was a prospective study. The initial clinical data (first month) included motor index, Ashworth scale, de Bats score for shoulder subluxation, Montgomery-Asberg Depression Rating Scale, and sensory disorders evaluation. The prognosis of CRPS I was evaluated from the Perrigot score. A score of CRPS I severity was measured on entry and 3 mo later.

Results: Of the 71 patients with hemiplegia who were included, 34.8% had a CRPS I. The five main clinical factors in the prognosis of CRPS I were motor deficit, spasticity, sensory deficits, and initial coma. The prognostic score of Perrigot was strongly correlated with the CRPS I severity and was predictive of subsequent progression.

Conclusion: Shoulder subluxation, unilateral neglect, and depression did not seem to be determinant predictive factors of CRPS I severity.

MeSH terms

  • Female
  • Hemiplegia / etiology
  • Hemiplegia / therapy*
  • Humans
  • Male
  • Prognosis
  • Prospective Studies
  • Reflex Sympathetic Dystrophy / classification
  • Reflex Sympathetic Dystrophy / therapy*
  • Severity of Illness Index
  • Stroke / complications