Fallopian tube cancer in a BRCA1 mutation carrier: rapid development and failure of screening

Am J Obstet Gynecol. 2002 Jan;186(1):53-4. doi: 10.1067/mob.2002.119187.

Abstract

We report a case of fallopian tube cancer that developed in a woman with a germ-line BRCA1 mutation. The notable feature of this case was the extremely rapid growth of the cancer, which precluded early diagnosis. Preventive gynecologic surgery in BRCA1/2 mutation carriers should probably always include bilateral salpingectomy.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / genetics*
  • Disease Progression
  • Fallopian Tube Neoplasms / genetics*
  • Female
  • Genes, BRCA1*
  • Genetic Testing*
  • Humans
  • Middle Aged
  • Mutation*
  • Pedigree
  • Time Factors