RNA processing: splicing and the cytoplasmic localisation of mRNA

Curr Biol. 2002 Jan 22;12(2):R50-2. doi: 10.1016/s0960-9822(01)00671-6.


An unexpected link has been discovered between pre-mRNA splicing in the nucleus and mRNA localisation in the cytoplasm. The new findings suggest that recruitment of the Mago Nashi and Y14 proteins upon splicing of oskar mRNA is an essential step in the localisation of the RNA to the posterior pole of the Drosophila oocyte.

Publication types

  • Review

MeSH terms

  • Animals
  • Cytoplasm / metabolism*
  • Drosophila
  • Oocytes / metabolism
  • RNA Processing, Post-Transcriptional*
  • RNA Splicing*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism*


  • RNA, Messenger