Histopathology of anterior lens capsules in vitrectomized eyes with tamponade by silicone oil

J Cataract Refract Surg. 2002 Feb;28(2):376-8. doi: 10.1016/s0886-3350(01)00957-9.


Histopathologic examination and immunohistochemistry for collagen type V were performed on residual anterior lens capsules of vitrectomized eyes (2 patients) that had been tamponaded with silicone oil. Many spaces, presumably occupied by oil droplets, were observed in connective tissue accumulations beneath the capsules. Immunoreactivity in the extracellular matrix for collagen type V was most marked adjacent to these spaces. These silicone droplets may delay capsule healing as collagen type V indicates immature connective tissue.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anterior Eye Segment
  • Collagen Type V / metabolism
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Lens Capsule, Crystalline / metabolism
  • Lens Capsule, Crystalline / pathology*
  • Male
  • Middle Aged
  • Silicone Oils / therapeutic use*
  • Vitrectomy*
  • Vitreoretinopathy, Proliferative / surgery


  • Collagen Type V
  • Silicone Oils