[Pharmacological study on the extracts from Typhonium flagelliforme Blume]

Zhong Yao Cai. 2001 Oct;24(10):735-8.
[Article in Chinese]


Objective: To study the pharmacological action of Typhonium flagelliforme Blune(TFB).

Methods: Relieving a cough and eliminating expectoration were observed by strong aqua spray and pheol red determining methods. The antiasthmatic action was observed by whole spraying method. The analgesia and anti-inflammation were studied by the twisting test induced by acetic acid and ear swelling induced by xylene. The sedation was determined by autonomic action test. The toxicity of TFB was studied through the acute toxicity test in mice.

Results: All the water, alcohol and ester extracts of TFB could significantly decrease cough times, increase phenol red outage in trachea, prolong asthma incubation period, decrease twisting times, inhibit ear swelling and decrease autonomic action times.

Conclusion: All water, alcohol and ester extracts of TFB have effects of relieving a cough, eliminating expectoration, antiasthmatic, analgesia, anti-inflammation and sedation. The maximum tolerances of TFB for acute toxicity were 720 g/kg(water extract), 900 g/kg (alcohol extract) 3240 g/kg(ester extract) respectively.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesics / pharmacology
  • Animals
  • Anti-Asthmatic Agents / pharmacology
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Antitussive Agents / pharmacology
  • Drugs, Chinese Herbal / pharmacology*
  • Drugs, Chinese Herbal / toxicity
  • Female
  • Hypnotics and Sedatives / pharmacology
  • Male
  • Mice
  • Pinellia / chemistry*


  • Analgesics
  • Anti-Asthmatic Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antitussive Agents
  • Drugs, Chinese Herbal
  • Hypnotics and Sedatives