Role of the B7-CD28/CTLA-4 pathway in autoimmune disease

Curr Dir Autoimmun. 2002;5:113-30. doi: 10.1159/000060550.
No abstract available

Publication types

  • Review

MeSH terms

  • Abatacept
  • Animals
  • Antibodies, Monoclonal / immunology
  • Antibodies, Monoclonal / therapeutic use
  • Antigens, CD / immunology*
  • Antigens, Differentiation / immunology*
  • Autoimmune Diseases / immunology*
  • Autoimmune Diseases / therapy
  • Autoimmunity / immunology
  • B7-1 Antigen / immunology*
  • B7-2 Antigen
  • CD28 Antigens / immunology*
  • CTLA-4 Antigen
  • Diabetes Mellitus, Type 1 / immunology
  • Diabetes Mellitus, Type 1 / therapy
  • Disease Models, Animal
  • Encephalomyelitis, Autoimmune, Experimental / immunology
  • Encephalomyelitis, Autoimmune, Experimental / therapy
  • Humans
  • Immune Tolerance / immunology
  • Immunoconjugates*
  • Immunoglobulin G / therapeutic use
  • Lymphocyte Activation / immunology
  • Membrane Glycoproteins / antagonists & inhibitors
  • Membrane Glycoproteins / immunology*
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred NOD
  • Mice, Knockout
  • Mice, Transgenic
  • Multiple Sclerosis
  • Signal Transduction / immunology*
  • T-Lymphocyte Subsets / cytology
  • T-Lymphocyte Subsets / immunology

Substances

  • Antibodies, Monoclonal
  • Antigens, CD
  • Antigens, Differentiation
  • B7-1 Antigen
  • B7-2 Antigen
  • CD28 Antigens
  • CD86 protein, human
  • CTLA-4 Antigen
  • CTLA4 protein, human
  • Cd86 protein, mouse
  • Ctla4 protein, mouse
  • Immunoconjugates
  • Immunoglobulin G
  • Membrane Glycoproteins
  • Abatacept