The role of TNF/TNFR in organ-specific and systemic autoimmunity: implications for the design of optimized 'anti-TNF' therapies

Curr Dir Autoimmun. 2002;5:30-50. doi: 10.1159/000060546.
No abstract available

Publication types

  • Review

MeSH terms

  • Amino Acid Motifs
  • Animals
  • Autoimmune Diseases / immunology
  • Autoimmune Diseases / metabolism
  • Autoimmunity / immunology*
  • Drug Design
  • Genetic Predisposition to Disease
  • Humans
  • Immune Tolerance
  • Lupus Erythematosus, Systemic / immunology
  • Lupus Erythematosus, Systemic / metabolism
  • Mice
  • Mice, Inbred Strains
  • Mice, Knockout
  • Mice, Mutant Strains
  • Models, Animal
  • Organ Specificity
  • Receptors, Tumor Necrosis Factor / antagonists & inhibitors
  • Receptors, Tumor Necrosis Factor / chemistry
  • Receptors, Tumor Necrosis Factor / classification
  • Receptors, Tumor Necrosis Factor / physiology*
  • Signal Transduction
  • T-Lymphocytes / immunology
  • Tumor Necrosis Factor-alpha / deficiency
  • Tumor Necrosis Factor-alpha / physiology*

Substances

  • Receptors, Tumor Necrosis Factor
  • Tumor Necrosis Factor-alpha