Clinical and functional target validation using tissue and cell microarrays

Curr Opin Chem Biol. 2002 Feb;6(1):97-101. doi: 10.1016/s1367-5931(01)00283-6.

Abstract

Expression levels of thousands of genes or proteins can be readily determined using microarray techniques. However, this represents only the first step in understanding the biological and medical significance of these molecules. New high-throughput techniques, such as tissue and cell microarrays, will facilitate clinical and functional analysis of molecular targets.

Publication types

  • Review
  • Validation Study

MeSH terms

  • Animals
  • Biotechnology / methods*
  • Cells / chemistry
  • Genome*
  • Humans
  • Miniaturization / methods
  • Oligonucleotide Array Sequence Analysis
  • Proteome / analysis*
  • Specimen Handling / methods

Substances

  • Proteome