Activation and inhibition of lymphocytes by costimulation

J Clin Invest. 2002 Feb;109(3):295-9. doi: 10.1172/JCI14941.
No abstract available

Publication types

  • Review

MeSH terms

  • Abatacept
  • Animals
  • Antigens, CD
  • Antigens, Differentiation / metabolism
  • Antigens, Differentiation, T-Lymphocyte / metabolism
  • B-Lymphocytes / immunology
  • CD28 Antigens / metabolism
  • CTLA-4 Antigen
  • Cyclic AMP / metabolism
  • Humans
  • Immunoconjugates*
  • Inducible T-Cell Co-Stimulator Protein
  • Ligands
  • Lymphocyte Activation*
  • Lymphocytes / immunology*
  • Lymphocytes / metabolism
  • Mice
  • Oncogene Proteins / metabolism
  • Phosphatidylinositol 3-Kinases / metabolism
  • Protein-Serine-Threonine Kinases*
  • Proto-Oncogene Proteins / metabolism
  • Proto-Oncogene Proteins c-akt
  • Proto-Oncogene Proteins c-vav
  • Signal Transduction
  • T-Lymphocytes / immunology

Substances

  • Antigens, CD
  • Antigens, Differentiation
  • Antigens, Differentiation, T-Lymphocyte
  • CD28 Antigens
  • CTLA-4 Antigen
  • CTLA4 protein, human
  • Ctla4 protein, mouse
  • ICOS protein, human
  • Icos protein, mouse
  • Immunoconjugates
  • Inducible T-Cell Co-Stimulator Protein
  • Ligands
  • Oncogene Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-vav
  • VAV1 protein, human
  • Vav1 protein, mouse
  • Abatacept
  • Cyclic AMP
  • Phosphatidylinositol 3-Kinases
  • Protein-Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt