Recurrent Pneumonia Due to Persistent Chlamydia Pneumoniae Infection

Intern Med. 2002 Jan;41(1):30-3. doi: 10.2169/internalmedicine.41.30.

Abstract

Two cases of recurrent pneumonia due to Chlamydia pneumoniae are described. C. pneumoniae was continuously detected from the nasopharynx in both patients by the polymerase chain reaction and/or culture even with appropriate antibiotic therapy during the first episode. After eradication of C. pneumoniae with long-term macrolide therapy, the respiratory symptoms of both patients completely disappeared and no relapse was observed. These data indicate that new treatment strategies may be necessary to eradicate the organism in patients prone to persistent infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use*
  • Chlamydia Infections / diagnostic imaging
  • Chlamydia Infections / drug therapy
  • Chlamydia Infections / microbiology*
  • Chlamydophila pneumoniae / isolation & purification*
  • Female
  • Humans
  • Macrolides
  • Male
  • Pneumonia, Bacterial / diagnostic imaging
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / microbiology*
  • Radiography
  • Recurrence
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Macrolides