Spontaneous clinical regression in chronic lymphocytic leukaemia

Br J Haematol. 2002 Feb;116(2):341-5.


Chronic lymphocytic leukaemia (CLL) is a B-cell disorder, which has a median survival of over 10 years from diagnosis for stage A disease. The natural history of stage A disease is generally indolent or only slowly progressive. It is less well known that CLL may undergo spontaneous regression. We report a series of 10 such cases (eight stage A and two stage B) followed at our institutions.

MeSH terms

  • Aged
  • Chromosomes, Human, Pair 12*
  • Female
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Male
  • Middle Aged
  • Remission, Spontaneous
  • Trisomy*