Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

Chem Biol. 2002 Jan;9(1):3-16. doi: 10.1016/s1074-5521(02)00092-3.
No abstract available

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Enzyme Inhibitors / metabolism*
  • Fungal Proteins / metabolism
  • Histone Deacetylase 1
  • Histone Deacetylase 2
  • Histone Deacetylase Inhibitors*
  • Histone Deacetylases / chemistry
  • Histone Deacetylases / genetics
  • Histone Deacetylases / metabolism
  • Histones / genetics
  • Histones / metabolism
  • Humans
  • Molecular Sequence Data
  • Protein Binding
  • Repressor Proteins*
  • Silent Information Regulator Proteins, Saccharomyces cerevisiae*
  • Sirtuin 1
  • Sirtuin 2
  • Sirtuins
  • Structure-Activity Relationship
  • Trans-Activators / antagonists & inhibitors*
  • Trans-Activators / chemistry
  • Trans-Activators / genetics
  • Trans-Activators / metabolism
  • Transcription, Genetic

Substances

  • Enzyme Inhibitors
  • Fungal Proteins
  • Histone Deacetylase Inhibitors
  • Histones
  • Repressor Proteins
  • Silent Information Regulator Proteins, Saccharomyces cerevisiae
  • Trans-Activators
  • SIR2 protein, S cerevisiae
  • SIRT1 protein, human
  • Sirtuin 1
  • Sirtuin 2
  • Sirtuins
  • HDAC1 protein, human
  • Histone Deacetylase 1
  • Histone Deacetylase 2
  • Histone Deacetylases