The skin-lightening effects of artocarpin on UVB-induced pigmentation

Planta Med. 2002 Jan;68(1):79-81. doi: 10.1055/s-2002-20057.

Abstract

This study was conducted to evaluate the effects of the prenylated flavonol artocarpin from the heartwood of Artocarpus incisus on ultraviolet (UV)-induced hyperpigmentation of guinea pig skin. An efficient lightening effect was observed following topical application of artocarpin to UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs.

Publication types

  • Letter

MeSH terms

  • Animals
  • Arbutin / pharmacology
  • Carrier Proteins / chemistry
  • Carrier Proteins / isolation & purification
  • Carrier Proteins / pharmacology*
  • Guinea Pigs
  • Lectins / chemistry
  • Lectins / isolation & purification
  • Lectins / pharmacology*
  • Male
  • Mannose-Binding Lectins*
  • Melanins / metabolism*
  • Melanins / radiation effects
  • Molecular Structure
  • Monophenol Monooxygenase / metabolism
  • Moraceae*
  • Plant Lectins
  • Pyrones / pharmacology
  • Skin Pigmentation / drug effects*
  • Skin Pigmentation / radiation effects
  • Ultraviolet Rays

Substances

  • Carrier Proteins
  • Lectins
  • Mannose-Binding Lectins
  • Melanins
  • Plant Lectins
  • Pyrones
  • artocarpin lectin
  • kojic acid
  • Arbutin
  • Monophenol Monooxygenase