A new coumarin from Murraya paniculata

Planta Med. 2002 Jan;68(1):81-3. doi: 10.1055/s-2002-19874.

Abstract

A new natural product, 2'-O-ethylmurrangatin (1) was isolated along with two previously known compounds murranganone (2) and paniculatin (3) from the leaves of Murraya paniculata. The structure of compound 1 was elucidated with the help of spectroscopic studies and by chemical reactions. Compounds 2 and 3 have been found to be cholinesterase inhibitors.

Publication types

  • Letter

MeSH terms

  • Acetylcholinesterase / metabolism
  • Butyrylcholinesterase / metabolism
  • Cholinesterase Inhibitors / chemistry
  • Cholinesterase Inhibitors / isolation & purification
  • Cholinesterase Inhibitors / pharmacology
  • Coumarins / chemistry*
  • Coumarins / isolation & purification
  • Coumarins / pharmacology*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Leaves / chemistry
  • Rutaceae*

Substances

  • 2'-O-ethylmurrangatin
  • Cholinesterase Inhibitors
  • Coumarins
  • Plant Extracts
  • murranganone
  • paniculatin
  • coumarin
  • Acetylcholinesterase
  • Butyrylcholinesterase