Cheilitis granulomatosa

J Eur Acad Dermatol Venereol. 2001 Nov;15(6):519-23. doi: 10.1046/j.1468-3083.2001.00353.x.


Cheilitis granulomatosa is a rare inflammatory disorder with unclear aetiology. It is a disorder characterized by recurrent or persistent swelling of one or both lips that may be part of the Melkersson-Rosenthal syndrome or may be a manifestation of Crohn's disease. An overview of the clinical features, histopathology, differential diagnosis, management strategies and prognosis of cheilitis granulomatosa is presented and discussed with regard to the literature.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Biopsy, Needle
  • Cheilitis / drug therapy*
  • Cheilitis / etiology*
  • Crohn Disease / complications*
  • Crohn Disease / diagnosis
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Melkersson-Rosenthal Syndrome / complications*
  • Melkersson-Rosenthal Syndrome / diagnosis
  • Prognosis
  • Steroids


  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Steroids