Seven single nucleotide substitutions in human Fc(gamma) receptor IIB gene

Tissue Antigens. 2001 Nov;58(5):339-42. doi: 10.1034/j.1399-0039.2001.580509.x.


Variation screening for the immunoglobulin G Fc receptor IIB (Fc(gamma)RIIB) gene was performed with the genomic DNA from 100 healthy Japanese subjects. We identified 3 non-synonymous and 2 synonymous substitutions and 2 single-nucleotide polymorphisms in an intron region. These substitutions were found to be located in the ligand-binding domain and the intron, which might alter the function of Fc(gamma)RIIb.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Motifs
  • Antigens, CD / chemistry
  • Antigens, CD / genetics*
  • Base Sequence
  • DNA Primers
  • Humans
  • Molecular Sequence Data
  • Polymorphism, Single Nucleotide*
  • Receptors, IgG / chemistry
  • Receptors, IgG / genetics*
  • Sequence Analysis, DNA


  • Antigens, CD
  • DNA Primers
  • Fc gamma receptor IIB
  • Receptors, IgG

Associated data

  • GENBANK/AB060144
  • GENBANK/AB060145
  • GENBANK/AB060146
  • GENBANK/AB060147
  • GENBANK/AB060148
  • GENBANK/AB060149
  • GENBANK/AB060150