Relapsing Exophiala Jeanselmei Phaeohyphomycosis in a Lung-Transplant Patient

Transpl Infect Dis. 2001 Dec;3(4):235-8. doi: 10.1034/j.1399-3062.2001.30408.x.

Abstract

Dematiaceous fungi are a cause of a variety of human infections, including phaeohyphomycosis, that may affect patients with solid organ or bone marrow transplants. Exophiala jeanselmei, the most common cause of the pheomycotic cyst/subcutaneous phaeohyphomycosis in the United States, has been shown to cause disease in transplant recipients. We report a lung-transplant patient with relapsing and invasive E. jeanselmei phaeohyphomycosis, who previously had a pheomycotic cyst excised and treated with oral fluconazole. The patient was subsequently treated with re-excision and an 8-month course of oral itraconazole without relapse as to date.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cysts / microbiology*
  • Cysts / surgery*
  • Dermatomycoses / drug therapy
  • Dermatomycoses / microbiology*
  • Exophiala / isolation & purification*
  • Humans
  • Itraconazole / therapeutic use
  • Lung Transplantation / adverse effects*
  • Male
  • Middle Aged

Substances

  • Itraconazole