Bronchiolitis: update 2001

Curr Opin Pulm Med. 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006.


In this review, reports from last year on the following topics are summarized: (1) reviews of bronchiolitis in infants; respiratory syncytial virus (RSV)-associated illness, including possible viral mechanisms of alteration of airway function and results of an epidemiologic study of bronchiolitis-associated mortality. Studies evaluating (2) the use of serum eosinophilic cationic protein as a marker for development of subsequent persistent wheezing infants; (3) parental bronchial responsiveness as an indicator of genetic susceptibility to acute bronchiolitis; (4) prophylactic use of monoclonal antibody (Palivizumab) to control an outbreak of RSV in a hospital nursery; (5) a controlled clinical trial of ribaviron in acutely ill children; (6) reports of new associations with bronchiolitis obliterans organizing pneumonia (BOOP); (7) case reports of use of methotrexate as an alternate to corticosteroids in treatment of BOOP; (8) a newly described entity, eosinophilic bronchiolitis.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Adrenal Cortex Hormones / administration & dosage
  • Age Distribution
  • Bronchiolitis, Viral / diagnosis*
  • Bronchiolitis, Viral / drug therapy
  • Bronchiolitis, Viral / epidemiology*
  • Child
  • Child, Preschool
  • Cryptogenic Organizing Pneumonia / diagnosis*
  • Cryptogenic Organizing Pneumonia / diet therapy*
  • Cryptogenic Organizing Pneumonia / epidemiology
  • Drug Therapy, Combination
  • Female
  • Humans
  • Infant
  • Male
  • Methotrexate / administration & dosage
  • Prevalence
  • Prognosis
  • Respiratory Syncytial Virus Infections / diagnosis*
  • Respiratory Syncytial Virus Infections / drug therapy
  • Respiratory Syncytial Virus Infections / epidemiology*
  • Risk Factors
  • Severity of Illness Index


  • Adrenal Cortex Hormones
  • Methotrexate