Argosomes: membrane fragments on the run

Trends Cell Biol. 2002 Feb;12(2):57-60. doi: 10.1016/s0962-8924(01)02227-9.

Abstract

Any biology student will know that the plasma membrane separates the inside of a cell from the outside world. Indeed, the plasma membrane is the guardian of a cell's physiology. Fewer students will be aware that cells can export bits of plasma membrane to distant sites in a tissue. Recent work demonstrates the transfer of membrane fragments in a live epithelium and, importantly, suggests that these fragments might be used as a vehicle to transport morphogens in a developing tissue.

Publication types

  • News

MeSH terms

  • Animals
  • Biological Transport
  • Cell Membrane / metabolism
  • Drosophila Proteins*
  • Drosophila melanogaster / metabolism
  • Endocytosis / physiology
  • Endosomes / metabolism*
  • Glycosylphosphatidylinositols / metabolism
  • Green Fluorescent Proteins
  • Luminescent Proteins / genetics
  • Luminescent Proteins / metabolism
  • Proto-Oncogene Proteins / metabolism*
  • Wnt1 Protein
  • rho GTP-Binding Proteins / metabolism

Substances

  • Drosophila Proteins
  • Glycosylphosphatidylinositols
  • Luminescent Proteins
  • Proto-Oncogene Proteins
  • Wnt1 Protein
  • wg protein, Drosophila
  • Green Fluorescent Proteins
  • rho GTP-Binding Proteins