DNA microarrays for malaria

Trends Parasitol. 2002 Jan;18(1):39-45. doi: 10.1016/s1471-4922(01)02153-5.


DNA microarrays are a powerful tool for the analysis of RNA and DNA composition on a whole-genome scale. The first applications of this technology in parasitology are in place. This review examines the various approaches to Plasmodium transcript-profiling that are being adopted using DNA microarray analysis and discusses additional strategies for obtaining and collating information relevant to the search for drug and vaccine candidates in malaria.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Drug Resistance / genetics
  • Gene Expression Profiling
  • Humans
  • Life Cycle Stages
  • Malaria, Falciparum / genetics*
  • Malaria, Falciparum / prevention & control
  • Oligonucleotide Array Sequence Analysis / methods*
  • Plasmodium / genetics*
  • Vaccination