Cutaneous anthrax associated with microangiopathic hemolytic anemia and coagulopathy in a 7-month-old infant

JAMA. 2002 Feb 20;287(7):869-74. doi: 10.1001/jama.287.7.869.

Abstract

A 7-month-old infant with cutaneous anthrax developed severe systemic illness despite early treatment with antibiotics. The infant displayed severe microangiopathic hemolytic anemia with renal involvement, coagulopathy, and hyponatremia. These findings are unusual with cutaneous anthrax, but have been described in illness resulting from spider toxin and may delay correct diagnosis. The systemic manifestations of the disease persisted for nearly a month despite corticosteroid therapy, but resolved.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Hemolytic / etiology*
  • Anthrax / blood
  • Anthrax / diagnosis*
  • Anthrax / pathology
  • Bacillus anthracis / isolation & purification*
  • Bioterrorism*
  • Bone Diseases, Infectious / diagnosis
  • Diagnosis, Differential
  • Disseminated Intravascular Coagulation / etiology*
  • Environmental Exposure
  • Humans
  • Hyponatremia / etiology
  • Infant
  • Male
  • New York City
  • Skin Diseases, Bacterial / blood
  • Skin Diseases, Bacterial / diagnosis*
  • Skin Diseases, Bacterial / pathology
  • Soft Tissue Infections / diagnosis
  • Spider Bites / diagnosis
  • Spores, Bacterial / isolation & purification
  • Thrombocytopenia / etiology