Towards the comprehension of genetic mechanisms controlling brain morphogenesis

Trends Neurosci. 2002 Mar;25(3):119-21. doi: 10.1016/s0166-2236(00)02095-6.


Over the past few years, a huge amount of work has provided mouse mutants for many genes required for regionalization of the developing brain. This remarkable work now offers the opportunity of unmasking new and unexpected gene functions that underlie a complex network of molecular interactions.

Publication types

  • Review

MeSH terms

  • Animals
  • Body Patterning / genetics*
  • Brain / embryology*
  • Brain / metabolism
  • Embryonic Induction / genetics*
  • Gene Expression Regulation, Developmental / genetics*
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / metabolism*
  • Mice
  • Mice, Neurologic Mutants / abnormalities*
  • Mice, Neurologic Mutants / genetics


  • Homeodomain Proteins