Total synthesis of isoroquefortine C

J Org Chem. 2002 Feb 8;67(3):620-4. doi: 10.1021/jo0106593.

Abstract

A short and efficient total synthesis of isoroquefortine C, the 3,12-(Z)-isomer of roquefortine C, from L-tryptophan methyl ester hydrochloride and 4(5)-(hydroxy)methylimidazole hydrochloride is described.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Ergolines / chemistry*
  • Heterocyclic Compounds, 4 or More Rings
  • Indoles*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Structure
  • Penicillium / chemistry
  • Piperazines
  • Spectrophotometry, Infrared

Substances

  • Ergolines
  • Heterocyclic Compounds, 4 or More Rings
  • Indoles
  • Piperazines
  • roquefortine