Microvascular complications in cystic fibrosis-related diabetes mellitus: a case report

JOP. 2000 Nov;1(4):208-10.


CONTEXT, The prevalence of cystic fibrosis-related diabetes mellitus is increasing and is associated with increased survival from cystic fibrosis. CASE REPORT, This study describes a case of the premature onset of disabling and widespread microvascular complications resulting from cystic fibrosis-related diabetes mellitus. Previously asymptomatic retinopathy was diagnosed on recognition of diabetic nephropathy. CONCLUSIONS, The treatment of pulmonary exacerbations has become more complex due to the nephrotoxic potential of intravenous aminoglycoside drugs which are frequently used to control chronic Pseudomonas infection in cystic fibrosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aminoglycosides
  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use
  • Cystic Fibrosis / physiopathology*
  • Diabetes Mellitus / physiopathology*
  • Diabetic Nephropathies / diagnosis
  • Female
  • Humans
  • Lactams
  • Microcirculation / physiopathology*
  • Pneumonia, Bacterial / blood
  • Pneumonia, Bacterial / diagnosis
  • Pneumonia, Bacterial / drug therapy
  • Pseudomonas Infections / diagnosis
  • Pseudomonas Infections / drug therapy
  • Renal Insufficiency / blood
  • Renal Insufficiency / diagnosis


  • Aminoglycosides
  • Anti-Bacterial Agents
  • Lactams