Improved glucose tolerance and insulin sensitivity after electrical stimulation-assisted cycling in people with spinal cord injury

Spinal Cord. 2002 Mar;40(3):110-7. doi: 10.1038/sj.sc.3101260.

Abstract

Design: Longitudinal training.

Objectives: The purpose was to determine the effect of electrical stimulation (ES)-assisted cycling (30 min/day, 3 days/week for 8 weeks) on glucose tolerance and insulin sensitivity in people with spinal cord injury (SCI).

Setting: The Steadward Centre, Alberta, Canada.

Methods: Seven participants with motor complete SCI (five males and two females aged 30 to 53 years, injured 3-40 years, C5-T10) underwent 2-h oral glucose tolerance tests (OGTT, n=7) and hyperglycaemic clamp tests (n=3) before and after 8 weeks of training with ES-assisted cycling.

Results: Results indicated that subjects' glucose level were significantly lower at 2 h OGTT following 8 weeks of training (122.4+/-10 vs 139.9+/-16, P=0.014). Two-hour hyperglycaemic clamps tests showed improvement in all three people for glucose utilisation and in two of three people for insulin sensitivity.

Conclusions: These results suggested that exercise with ES-assisted cycling is beneficial for the prevention and treatment of Type 2 diabetes mellitus in people with SCI.

Sponsorship: Supported by Alberta Paraplegic Foundation, Therapeutic Alliance.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose / analysis*
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Electric Stimulation Therapy / methods*
  • Female
  • Glucose Tolerance Test
  • Humans
  • Insulin Resistance
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Paraplegia / metabolism
  • Paraplegia / rehabilitation
  • Probability
  • Prospective Studies
  • Quadriplegia / metabolism
  • Quadriplegia / rehabilitation
  • Sensitivity and Specificity
  • Spinal Cord Injuries / metabolism*
  • Spinal Cord Injuries / rehabilitation*

Substances

  • Blood Glucose