Objective: To study the therapeutic effects of transcatheter arterial chemoembolization (TACE) combined with beta-ultrasound guided percutaneous ethanol injection (PEI) at multiple points for hepatocellular carcinoma.
Methods: Eighty-seven patients with hepatocellular carcinoma were divided into two groups: Group A, 45 patients were treated with TACE only, group B, 42 patients were treated with TACE plus PEI.
Results: In group A patients, the 1-, 2-, and 3-year survival rates were 66.7%, 41.4%, and 21.4%, respectively. Only 26.1% of cancer specimens showed complete necrosis by pathologic examination in group A. In group B, the 1-, 2-, and 3-year survival rates were 97.1%, 85.71% and 65.71%, respectively, with complete necrosis in 81.8%.
Conclusion: The therapeutic effects of transcatheter arterial chemoembolization combined with percutaneous multiple point ethanol injection through liver puncture is much better than that of TACE alone.