Acid-base and electrolyte management in continuous renal replacement therapy

Blood Purif. 2002;20(3):262-8. doi: 10.1159/000047018.


Continuous renal replacement techniques are often utilized to manage acid-base and electrolyte problems in the critically ill patient. These techniques have an inherent capacity to manipulate the plasma composition and can be utilized efficiently to maintain homeostasis and metabolic control. Unfortunately, the efficacy of these techniques also permits wide variation in their use and can result in complications if they are not used appropriately. In most instances complications can be prevented by recognition of the operating principles and careful attention to detail. This article provides an overview of the principles of acid-base and electrolyte management with continuous renal replacement therapy.

Publication types

  • Review

MeSH terms

  • Acid-Base Equilibrium / physiology
  • Acute Kidney Injury / complications
  • Acute Kidney Injury / therapy
  • Hemodialysis Solutions / chemistry
  • Hemodialysis Solutions / metabolism*
  • Hemodialysis Solutions / standards
  • Humans
  • Renal Replacement Therapy / adverse effects
  • Renal Replacement Therapy / methods*
  • Renal Replacement Therapy / standards
  • Water-Electrolyte Balance / physiology


  • Hemodialysis Solutions