Rapidly expanding lung abscess caused by Legionella pneumophila in immunocompromised patients: a report of two cases

Intern Med. 2002 Feb;41(2):133-7. doi: 10.2169/internalmedicine.41.133.

Abstract

We describe two cases of lung abscess caused by Legionella pneumophila in immunocompromised patients. The first case had been treated initially with 60 mg prednisolone for ulcerative colitis, and L. pneumophila serogroup 1 was isolated from sputum samples after cavitation of the lung lesion. The second case was diagnosed as plasma cell lymphoma at post-mortem examination. L. pneumophila serogroup 5 was isolated from the contents of lung abscess, together with Enterococcus faecium and Prevotella intermedia in the post-mortem examination. Lung abscess caused by Legionella is unusual. Here, we discuss the difficulty of diagnosis of legionellosis in patients with unusual chest radiographic findings.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Bacteroidaceae Infections / complications
  • Bacteroidaceae Infections / microbiology
  • Colitis, Ulcerative / complications
  • Colitis, Ulcerative / drug therapy
  • Enterococcus faecium / isolation & purification
  • Fatal Outcome
  • Female
  • Gram-Positive Bacterial Infections / complications
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Immunocompromised Host
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Legionella pneumophila / isolation & purification
  • Legionnaires' Disease / complications*
  • Legionnaires' Disease / diagnostic imaging
  • Legionnaires' Disease / transmission
  • Lung Abscess / diagnostic imaging
  • Lung Abscess / etiology*
  • Lung Abscess / microbiology
  • Lymphoma / complications
  • Male
  • Prednisolone / adverse effects
  • Prednisolone / therapeutic use
  • Prevotella intermedia / isolation & purification
  • Radiography

Substances

  • Immunosuppressive Agents
  • Prednisolone