Tuberous sclerosis

Cutis. 2002 Feb;69(2):103-9.


Tuberous sclerosis (TS) is an autosomal dominant disorder with a significant range of clinical expression. Renal, pulmonary, central nervous system, and cardiac complications may result in severe morbidity. Early recognition of the syndrome is important to ensure prompt identification of systemic involvement. We review the clinical features of tuberous sclerosis and discuss recent advances in our understanding of its pathogenesis and appropriate management.

Publication types

  • Review

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Child
  • Facial Dermatoses / diagnosis
  • Facial Dermatoses / epidemiology
  • Facial Dermatoses / therapy
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prognosis
  • Risk Factors
  • Severity of Illness Index
  • Sex Distribution
  • Tuberous Sclerosis / diagnosis*
  • Tuberous Sclerosis / epidemiology
  • Tuberous Sclerosis / therapy*