Catalytic hydrophosphination of styrenes

Mstislav O Shulyupin; Marina A Kazankova; Irina P Beletskaya

doi:10.1021/ol017238s

Catalytic hydrophosphination of styrenes

Org Lett. 2002 Mar 7;4(5):761-3. doi: 10.1021/ol017238s.

Authors

Mstislav O Shulyupin¹, Marina A Kazankova, Irina P Beletskaya

Affiliation

¹ Department of Chemistry, Moscow State University, Leninskie Gory, GSP-3 Moscow, Russian Federation.

PMID: 11869121
DOI: 10.1021/ol017238s

Abstract

[reaction: see text] The first example of intermolecular hydrophosphination of styrenes catalyzed by Ni and Pd complexes is described. The reaction of Ph2PH with styrene, 4-vinylpyridine, 2-vinylpyridine, 4-methoxystyrene, 2-methoxystyrene, and 5-vinyl-2-methylpyridine in benzene under Ni[P(OEt)3]4 catalysis proceeds with high yield and selectivity to give only anti-Markovnikov product.