Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies

J Med Chem. 2002 Mar 14;45(6):1151-75. doi: 10.1021/jm010066k.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkenes / chemistry
  • Alkenes / pharmacology
  • Alkenes / therapeutic use
  • Antibiotics, Antineoplastic / chemistry
  • Antibiotics, Antineoplastic / pharmacology
  • Antibiotics, Antineoplastic / therapeutic use
  • Antifungal Agents / chemistry
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Cantharidin / chemistry
  • Cantharidin / therapeutic use
  • Crystallography, X-Ray
  • Cyclosporine / chemistry
  • Cyclosporine / pharmacology
  • Cyclosporine / therapeutic use
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Enzyme Inhibitors / therapeutic use
  • Humans
  • Microcystins
  • Models, Molecular
  • Okadaic Acid / chemistry
  • Okadaic Acid / pharmacology
  • Okadaic Acid / therapeutic use
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / pharmacology
  • Peptides, Cyclic / therapeutic use
  • Phosphoprotein Phosphatases / antagonists & inhibitors*
  • Phosphoprotein Phosphatases / metabolism
  • Polyenes
  • Pyrans*
  • Pyrones
  • Spiro Compounds*
  • Structure-Activity Relationship

Substances

  • Alkenes
  • Antibiotics, Antineoplastic
  • Antifungal Agents
  • Enzyme Inhibitors
  • Microcystins
  • Peptides, Cyclic
  • Polyenes
  • Pyrans
  • Pyrones
  • Spiro Compounds
  • tautomycin
  • Okadaic Acid
  • Cyclosporine
  • cyanoginosin-LA
  • Phosphoprotein Phosphatases
  • Cantharidin
  • fostriecin