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Review
, 76 (7), 3089-94

Destiny of Unspliced Retroviral RNA: Ribosome and/or Virion?

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Review

Destiny of Unspliced Retroviral RNA: Ribosome and/or Virion?

Melinda Butsch et al. J Virol.

Figures

FIG. 1.
FIG. 1.
(Model 1) The unspliced genome-length RNA (gray lines with intronic sequences denoted in black) achieves nuclear export and segregates into functionally distinct populations of either mRNA template for translation of viral proteins on host cell ribosomes or genomic RNA that is packaged into assembling virions. (Model 2A) The genome-length RNA can function interchangeably as both mRNA and genomic RNA with no requirement for prior translation. (Model 2B) Prior translation is a requirement for generation of genomic RNA.

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